| Popis: |
Background: Epicardial adipose tissue (EAT) is a kind of visceral adipose tissue with close proximity to coronary artery and myocardium, which can secrete cell factor, and influence the physiological function and pathophysiological process of myocardium and coronary artery. Clinical imaging diagnosis showed that the volume and thickness of epicardial adipose tissue exists a certain relevance with coronary artery disease, but it lacked evidence of evidence based medicine. The research on the implementation of this program will systematically evaluate the relationship of CT quantitative epicardial adipose tissue and coronary artery disease. Method: The English databases (Embase, PubMed, the Cochrane Library, Web of Science) and Chinese database (CNKI, Wanfang, China biomedical database, VIP) of computer retrieval has collected the case control clinical study of relationship between epicardial adipose tissue and coronary artery disease from the establishment of the database to October 2020, which was conducted extraction and quality evaluation by two researchers independently for data included in the study, and was conducted Meta analysis for the included literature by adopting RevMan5.3 software. Result: The research evaluated the correlation between epicardial adipose tissue and coronary artery disease through the epicardial adipose tissue thickness, epicardial adipose tissue volume and other indexes. Conclusion: The research has provided reliable evidence-based evidence for the correlation between CT epicardial adipose tissue quantification and coronary artery disease. |
