Treatment in a specialised out-patient mood disorder clinicv.standard out-patient treatment in the early course of bipolar disorder: randomised clinical trial
| Autor: | Hanne Vibe Hansen, Ellen Margrethe Christensen, Lars Vedel Kessing, Henrik Dam, Anne Hvenegaard, Christian Gluud, Jørn Wetterslev |
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| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Pediatrics business.industry Standard treatment medicine.medical_treatment Hazard ratio medicine.disease 030227 psychiatry law.invention 03 medical and health sciences Psychiatry and Mental health 0302 clinical medicine Mood Randomized controlled trial law Physical therapy medicine Psychiatric hospital Bipolar disorder medicine.symptom business Antipsychotic Mania 030217 neurology & neurosurgery |
| Zdroj: | British Journal of Psychiatry. 202:212-219 |
| ISSN: | 1472-1465 0007-1250 |
| DOI: | 10.1192/bjp.bp.112.113548 |
| Popis: | BackgroundLittle is known about whether treatment in a specialised out-patient mood disorder clinic improves long-term prognosis for patients discharged from initial psychiatric hospital admissions for bipolar disorder.AimsTo assess the effect of treatment in a specialised out-patient mood disorder clinicv.standard decentralised psychiatric treatment among patients discharged from one of their first three psychiatric hospital admissions for bipolar disorder.MethodPatients discharged from their first, second or third hospital admission with a single manic episode or bipolar disorder were randomised to treatment in a specialised out-patient mood disorder clinic or standard care (ClinicalTrials.gov: NCT00253071). The primary outcome measure was readmission to hospital, which was obtained from the Danish Psychiatric Central Register.ResultsA total of 158 patients with mania/bipolar disorder were included. The rate of readmission to hospital was significantly decreased for patients treated in the mood disorder clinic compared with standard treatment (unadjusted hazard ratio 0.60, 95% CI 0.37–0.97,P=0.034). Patients treated in the mood disorder clinic more often used a mood stabiliser or an antipsychotic and satisfaction with treatment was more prevalent than among patients who received standard care.ConclusionsTreatment in a specialised mood disorder clinic early in the course of bipolar disorder substantially reduces readmission to a psychiatric hospital and increases satisfaction with care. |
| Databáze: | OpenAIRE |
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