Місце назальних деконгестантів у лікуванні гострих інфекційних ринітів у дітей
| Autor: | L.L. Petrenko, A.E. Abaturov, V.L. Babich, E.A. Agafonova |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Mucociliary clearance business.industry Oxymetazoline Mucous membrane of nose Pathogenesis Nasal decongestant 03 medical and health sciences 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure medicine Etiology General Earth and Planetary Sciences Respiratory system 030223 otorhinolaryngology Intensive care medicine business General Environmental Science medicine.drug Respiratory tract |
| Zdroj: | CHILD`S HEALTH. 13:691-697 |
| ISSN: | 2307-1168 2224-0551 |
| DOI: | 10.22141/2224-0551.13.7.2018.148923 |
| Popis: | Acute infectious rhinosinusitis is the most common clinical form of respiratory pathology in childhood. Despite the fact that in 90 % of cases the main etiological factor leading to the development of rhinosinusitis is viral infection, 13 % of them are complicated by bacterial inflammation. Acute respiratory diseases with manifestations of rhinosinusitis constantly recurring in the child can lead to the formation of allergic, non-allergic rhinitis and chronic rhinosinusitis — multifactorial chronic inflammatory diseases of the upper respiratory tract. The pathogenesis of acute infectious rhinosinusitis, in spite of the abundance of data, has been underinvestigated. The article highlights the problem of acute infectious rhinosinusitis treatment in children from the standpoint of modern ideas about the development of inflammatory process in the nasal mucosa, the role of innate immunity, and the functioning of mucociliary clearance. Data on the clinical manifestations of acute infectious rhinosinusitis are presented, clinical and diagnostic criteria for its detection are given. The mechanisms of action of nasal decongestants are described, as well as the features of their use, the immunological and anti-inflammatory effects of these drugs. Attention is focused on the mechanisms of action of oxymetazoline. Recommendations for the use of oxymetazoline in pediatric practice are given. |
| Databáze: | OpenAIRE |
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