Central nervous system complications of children with acute leukemia
Autor: | Anna Mitus, Audrey E. Evans, Giulio J. D'Angio |
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Rok vydání: | 1964 |
Předmět: |
medicine.medical_specialty
Acute leukemia medicine.diagnostic_test Lumbar puncture business.industry Central nervous system Meninges Spinal cord medicine.disease Surgery Leukemia medicine.anatomical_structure Spinal Puncture Anesthesia Pediatrics Perinatology and Child Health medicine Methotrexate business medicine.drug |
Zdroj: | The Journal of Pediatrics. 64:94-96 |
ISSN: | 0022-3476 |
DOI: | 10.1016/s0022-3476(64)80323-1 |
Popis: | Comparable groups of patients with leukemic involvement of the central nervous system were treated by lumbar puncture alone, by the intrathecal administration of methotrexate, or by x-ray therapy. Methotrexate or x-ray therapy gave the best results and were equally effective. The side effects of x-ray, such as alopecia, to make intrathecal methotrexate the treatment of choice although indications for x-ray treatment or a combination of methotrexate and x-ray therapy are sometimes present. |
Databáze: | OpenAIRE |
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