Central nervous system complications of children with acute leukemia

Autor: Anna Mitus, Audrey E. Evans, Giulio J. D'Angio
Rok vydání: 1964
Předmět:
Zdroj: The Journal of Pediatrics. 64:94-96
ISSN: 0022-3476
DOI: 10.1016/s0022-3476(64)80323-1
Popis: Comparable groups of patients with leukemic involvement of the central nervous system were treated by lumbar puncture alone, by the intrathecal administration of methotrexate, or by x-ray therapy. Methotrexate or x-ray therapy gave the best results and were equally effective. The side effects of x-ray, such as alopecia, to make intrathecal methotrexate the treatment of choice although indications for x-ray treatment or a combination of methotrexate and x-ray therapy are sometimes present.
Databáze: OpenAIRE