Efficacy and Safety of Different Antimycotic Formulas Used in Sheep Frozen Semen Extenders
| Autor: | Helmy A. Torky, Hossam R. Kotb, Diya A. El-Badry, Mahmoud I. Mohamed, Mona H. Shaker, Fadwa M. Othman |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
endocrine system
Semen urologic and male genital diseases Andrology Semen quality fluids and secretions 0502 economics and business medicine Food science Candida albicans Cryptococcus neoformans biology urogenital system Clotrimazole business.industry 05 social sciences 0402 animal and dairy science 04 agricultural and veterinary sciences General Medicine biology.organism_classification 040201 dairy & animal science Sperm Nystatin 050211 marketing business Fluconazole medicine.drug |
| Zdroj: | Alexandria Journal of Veterinary Sciences. 48:77 |
| ISSN: | 1110-2047 |
| DOI: | 10.5455/ajvs.202266 |
| Popis: | This study aimed to select a potent and safe antimycotic as additive to cryodiluents of sheep frozen semen. Semen samples were collected from 6 Barki rams and processed for cryopreservation after adding different concentrations of griseovulvin, clotrimazole, nystatin, fluconazole or amphotricin-B to semen diluent. Sensitivity of Candida albicans and Cryptococcus neoformans to antimycotic drugs were studied. Results showed that fluconazole and nystatin (at dose not higher than 50 mg/L) had no deleterious effect on sheep semen freezability. Higher doses of amphotricin-B and griseofulvin resulted in drastic deterioration of frozen semen quality. Candida albicans and Cryptococcus neoformans were sensitive to fluconazole and amphotricin-B and resistant to lower concentrations of griseovulvin and clotrimazole. Conclusively, addition of fluconazole to sheep semen diluent has a benefit of improving the quality of yeast contaminated sperm with no bad effect on the frozen-thawed semen quality. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|