Lipase-Catalyzed Esterification
| Autor: | Sudhirprakash B. Sawant, Neena N. Gandhi, D. Mukesh, Jyeshtharaj B. Joshi, Nitin Sopanrao Patil, Pramod P. Wangikar |
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| Rok vydání: | 2000 |
| Předmět: | |
| Zdroj: | Catalysis Reviews. 42:439-480 |
| ISSN: | 1520-5703 0161-4940 |
| DOI: | 10.1081/cr-100101953 |
| Popis: | Lipases are versatile catalysts. In addition to their natural reaction of fat hydrolysis, lipases catalyze a plethora of other reactions such as esterification, amidation, and transesterification of esters as well as organic carbonates. Moreover, lipases accept a wide variety of substrates while maintaining their regioselectivity and stereoselectivity. Lipases are highly stable even under adverse conditions such as organic solvents, high temperatures, and so forth. Applications of lipases include production of food additives, chiral intermediates, and pharmaceutical products. Among these, synthesis of various chiral intermediates in pharmaceutical industry and cocoa butter substitutes is being commercially exploited currently. Lipase-catalyzed esterification and transesterification in anhydrous media (e.g., organic solvents and supercritical fluids) has been an area of major research activity in the past decade or so. Absence of water eliminates the competing hydrolysis reaction. Moreover, substrate speci... |
| Databáze: | OpenAIRE |
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