Effect of hydrocortisone on the liver cytochrome P-450 system and intensity of food anaphylaxis in guinea pigs
| Autor: | Khlopushina Tg, Marokko In, Shaternikov Va, Lysenkova Em, Kovalev Ie |
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| Rok vydání: | 1984 |
| Předmět: |
medicine.medical_specialty
Cytochrome biology Chemistry medicine.medical_treatment Intraperitoneal injection General Medicine Microsomal Monooxygenase General Biochemistry Genetics and Molecular Biology Endocrinology In vivo Internal medicine Food anaphylaxis medicine biology.protein Hydrocortisone medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 98:1699-1702 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00802959 |
| Popis: | Intraperitoneal injection of hydrocortisone in single daily doses from 0.1 to 25.0 mg/kg, for 3 days was followed by reduced activity of liver microsomal monooxygenases and decreased content of cytochrome P-450 and b5. Hydrocortisone diminished the activity of the liver cytochrome P-450 system in vivo that significantly potentiated hexenal sleep. The hydrocortisone-inhibited activity of the liver chromosome P-450 system was followed by intensified food anaphylaxis in guinea-pigs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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