Autor:	Toru Okubo, Ryuhei Hayashi, Yuji Kudo, Yuki Ishikawa, Andrew J. Quantock
Rok vydání:	2022
Popis:	We have established a method for producing three-dimensional lacrimal gland-like tissue organoids from human pluripotent stem cells (hPSCs). These resemble native lacrimal glands on the basis of their morphology, immuno-labelling characteristics and gene expression patterns. When transplanted into the connective tissue above the eyes of recipient rats the organoids undergo functional maturation, producing tear film proteins.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::247c29b7c585aba3a9a39a0b2657c160 https://doi.org/10.21203/rs.3.pex-1821/v1 Zobrazit plný text záznamu