| Autor: |
Xin Qi, Xian-Shu Gao, Xiao-mei Li, Shang-bin Qin, Xiao-ying Li, Ming-wei Ma, Yun Bai, Jia-yan Chen, Xue-ying Ren, Hong-zhen Li |
| Rok vydání: |
2022 |
| DOI: |
10.21203/rs.3.rs-2343333/v1 |
| Popis: |
Purpose It is indicated by prostatectomy specimens that the proximal 1- to 2-cm seminal vesicles (SVs) be irradiated in radiotherapy for prostate cancer with intermediate- to high-risk factors. However, patients usually receive neo-adjuvant hormonal therapy (NHT) before radiotherapy. The purpose of this study is to clarify the length and volume reduction of SVs after NHT, and to help contour the optimal SV included into high-dose clinical target volume (CTV) for radiotherapy in intermediate- and high-risk patients. Methods and Materials: MR images both before and after NHT (5.3 ± 2.2 months) were collected from thirty-one patients with cT2-4N0M0 prostate cancer. SV volume was measured in axial T1WI, while SV length was obtained in a reconstructed oblique coronary plane through its long axial from a 3D sequence. Results SVs showed evident reduction both in length and volume (length: median 12.1%, range 4.0–28.0%, volume: median 39.9%, range 9.4%-66.2%). For SVs with and without MR detected involvement, length shortening were 16.7 ± 4.8% and 11.1 ± 4.4% (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
