Characterization of an ovarian carcinoma cell line

Autor:	E. Pihl, C. Kusyk, H. S. Gallager, Ralph S. Freedman, Felix N. Rutledge
Rok vydání:	1978
Předmět:	Cancer Research Pathology medicine.medical_specialty Monosomy Cancer Karyotype Biology medicine.disease biology.organism_classification Transplantation Nude mouse Oncology Ovarian carcinoma medicine Histopathology Trisomy
Zdroj:	Cancer. 42:2352-2359
ISSN:	1097-0142 0008-543X
DOI:	10.1002/1097-0142(197811)42:5<2352::aid-cncr2820420536>3.0.co;2-#
Popis:	A long-term ovarian carcinoma cell line is described in terms of its morphology, original histopathology, electron microscopic features and chromosome features before and after transplantation into an athymic nude mouse. The microscopic features of the tumor nodule grown in the nude mouse are compared with the original pathology. Epithelial characteristics of the cells were maintained in culture and after retrieval from the nude mouse. Three markers were identified in all karyotypes and trisomy was noted in chromosomes 1, 2, 3, 6, 11, 12, 16, and × and monosomy of 17 and 21. Cancer 42:2352–2359, 1978.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2478293a5986c51c9b84ac9e8d07799f https://doi.org/10.1002/1097-0142(197811)42:5<2352::aid-cncr2820420536>3.0.co Zobrazit plný text záznamu Plný text