Sedation in a patient with William Syndrome without supravalvular aortic stenosis and normal QT: Challenge still remains
| Autor: | Rahul Kanjilal, Habib Md Reazaul Karim, Roma Sharma, Omer Mohammed Mujahid |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
biology business.industry Sedation Hemodynamics William syndrome Critical Care and Intensive Care Medicine Sudden death Anesthesiology and Pain Medicine Internal medicine Cardiology biology.protein Endocrine system Medicine medicine.symptom business Elastin Supravalvular aortic stenosis Mace |
| Zdroj: | Anaesthesia, Pain & Intensive Care. 24 |
| ISSN: | 2220-5799 1607-8322 |
| DOI: | 10.35975/apic.v24i3.1290 |
| Popis: | William Syndrome (WS) is a rare genetic condition related to deletion of elastin gene resulting in distinctive facies, cardiovascular diseases, learning difficulties, developmental delay, unique personality characteristics, endocrine involvement, etc.1 Although successful anaesthesia is reported, literature review indicate significant major adverse cardiac events (MACE) including sudden death, as frequent.2 So anaesthetic management of these patients has proved to be challenging. The cardiovascular abnormality, corrected QT, and cardio-depressant actions of anaesthetic drugs need critical considerations. |
| Databáze: | OpenAIRE |
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