One-Pot, Metal- and Azide-Free Synthesis of 1,2,3-Triazoles from α-Ketoacetals and Amines

Autor: Zehnder Luke Raymond, Sutton Scott Channing, Joel M. Hawkins
Rok vydání: 2019
Předmět:
Zdroj: Synlett. 31:175-178
ISSN: 1437-2096
0936-5214
DOI: 10.1055/s-0039-1691526
Popis: An efficient one-pot two-step synthesis of 1,4-disubstituted 1,2,3-triazoles from α-ketoacetals and amines is presented. The method does not use metals, azides, or oxidants, and is compatible with a variety of functional groups, including heterocycles, esters, nitriles, and carbamates.
Databáze: OpenAIRE