One-Pot, Metal- and Azide-Free Synthesis of 1,2,3-Triazoles from α-Ketoacetals and Amines
Autor: | Zehnder Luke Raymond, Sutton Scott Channing, Joel M. Hawkins |
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Rok vydání: | 2019 |
Předmět: | |
Zdroj: | Synlett. 31:175-178 |
ISSN: | 1437-2096 0936-5214 |
DOI: | 10.1055/s-0039-1691526 |
Popis: | An efficient one-pot two-step synthesis of 1,4-disubstituted 1,2,3-triazoles from α-ketoacetals and amines is presented. The method does not use metals, azides, or oxidants, and is compatible with a variety of functional groups, including heterocycles, esters, nitriles, and carbamates. |
Databáze: | OpenAIRE |
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