Silica-sulfuric acid: a highly efficient catalyst for the synthesis of imidazo[1,2-a]pyridines using trimethysilyl cyanide or cyanohydrins

Autor:	Leonid G. Voskressensky, Anatoliy I. Polyakov, Vera A. Eryomina, Nadezhda I. Tihonova, Lidiya A. Medvedeva, Anna V. Listratova
Rok vydání:	2009
Předmět:	chemistry.chemical_compound chemistry Cyanide Organic Chemistry Drug Discovery Condensation Silica sulfuric acid Organic chemistry Trimethylsilyl cyanide Efficient catalyst Biochemistry Catalysis
Zdroj:	Tetrahedron Letters. 50:4389-4393
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2009.05.080
Popis:	This Letter describes a novel synthetic approach towards imidazo[1,2- a ]pyridines via a three-component condensation using trimethylsilyl cyanide (TMSCN) or cyanohydrins as the source of CN − ions and silica-sulfuric acid as the catalyst.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::247114b73a212a62cbbf644880a86902 https://doi.org/10.1016/j.tetlet.2009.05.080 Zobrazit plný text záznamu Full Text from ScienceDirect