Twelve-Month Outcome in Bipolar Patients With and Without Personality Disorders

Autor: Brian J. McConville, Stephen M. Strakowski, Susan L. McElroy, Michael T. Sorter, Eduardo Dunayevich, Paul E. Keck, Kenji W. Sax
Rok vydání: 2000
Předmět:
Zdroj: The Journal of Clinical Psychiatry. 61:135-140
ISSN: 0160-6689
DOI: 10.4088/jcp.v61n0209
Popis: Background: We studied the 12-month course of illness after hospitalization for patients with a DSM-III-R diagnosis of bipolar disorder, manic or mixed episode, to identify the impact of a co-occurring personality disorder on measures of outcome. Method: Fifty-nine patients with bipolar disorder hospitalized for the treatment of a manic or mixed episode were recruited. Diagnostic, symptomatic, and functional evaluations were obtained at the index hospitalization. Personality disorders were assessed using the Structured Clinical Interview for DSM-III-R, personality disorders version (SCID-II). Patients were then reevaluated at 2, 6, and 12 months after discharge to assess syndromic, symptomatic, and functional recovery. Factors associated with outcome were identified using multivariate analyses. Results: Survival analyses showed that in the 12-month follow-up period, subjects with bipolar disorder and co-occurring personality disorder were significantly less likely to achieve recovery. Logistic regression analyses indicated that both a diagnosis of personality disorder and noncompliance with treatment were significantly associated with lack of syndromic recovery. Conclusion: Co-occurring personality disorders in patients with bipolar disorder are associated with poor outcome after hospitalization for mania.
Databáze: OpenAIRE