Sialadenitis of Unknown Etiology
Autor: | Rohan R. Walvekar, Miranda Lindburg, Allison Ogden |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
business.industry Amyloidosis Lymphoproliferative disorders medicine.disease Dermatology Sialadenitis 03 medical and health sciences 0302 clinical medicine Otorhinolaryngology 030220 oncology & carcinogenesis Major Salivary Gland Etiology medicine Immunology and Allergy Inflammatory pseudotumor Surgery Kimura Disease Neurology (clinical) 030223 otorhinolaryngology business Rosai–Dorfman disease |
Zdroj: | Current Otorhinolaryngology Reports. 9:378-382 |
ISSN: | 2167-583X |
Popis: | Most sialadenitis is attributed to infection, obstruction, or underlying autoimmunity; however, there are several rare processes affecting the salivary glands without clear etiology. We review the available literature, specifically addressing presentation, evaluation, and treatment. Juvenile recurrent parotitis is a typically self-limiting entity occurring in school-age children and may be benefitted by sialendoscopy. Sclerosing polycystic adenosis is a rare cystic disorder of major salivary glands, diagnosed, and treated through surgery. Inflammatory pseudotumor is thought to be an abnormal focal immune response, mimicking a neoplasm. Rosai-Dorfman and Kimura diseases are considered lymphoproliferative disorders, and amyloidosis is a rare protein deposition disorder; all of which can affect the salivary glands. Unusual clinical entities should be considered for atypical or persistent sialadenitis of unknown etiology. Work-up generally includes biopsy for histologic diagnosis. Treatment is typically supportive and/or related to treating associated systemic disease. Surgical excision is reserved to establish diagnosis, for severe/refractory cases, or when malignancy is suspected. |
Databáze: | OpenAIRE |
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