Pathophysiological response to experimental oral overdose of different forms of selenium in lambs

Autor: Alma Revilla-Vázquez, Martín F. Montaño-Gómez, Raquel López-Arellano, Jaime Jaimes-Miranda, J. Efrén Ramírez-Bribiesca, Jorge Tórtora-Pérez, Gabriela Rodríguez-Patiño
Rok vydání: 2015
Předmět:
Zdroj: Annals of Animal Science. 15:655-666
ISSN: 2300-8733
Popis: Twelve male lambs (30.5±2.1 kg) with cannulas in the rumen were divided into three groups to evaluate the accidental toxicity of selenium (Se) via digestive tract. The first group received intraruminal bolus without a Se source; the second group received intraruminal bolus with sodium selenite (SS: Na2SeO3); the third group received intraruminal bolus with barium selenate (BS: BaSeO4). The ruminal boluses were immediately degraded by a manufacturing defect, releasing an amount of 366 mg Se via rumen. All lambs had tachypnea (80 cycles per minute), a metallic smell in the oral cavity and laminitis foot. Analyses of necropsy and histopathology showed frequencies of lesions in the myocardium and skeletal muscle, lesions in the myocardium were more common in lambs intoxicated with SS or BS than the control group (P
Databáze: OpenAIRE