A soft and transparent contact lens for the wireless quantitative monitoring of intraocular pressure
| Autor: | Jihun Park, Junmo Kim, Eunkyung Cha, Dai Woo Kim, Joohee Kim, Taek-Soo Kim, Minjae Ku, Young Geun Park, Kyoung-Pil Lee, Hong Kyun Kim, Man-Il Huh, Jang Ung Park, Hyeon Seok An |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Intraocular pressure genetic structures Computer science Biomedical Engineering Medicine (miscellaneous) Glaucoma Bioengineering Integrated circuit law.invention 03 medical and health sciences 0302 clinical medicine law medicine medicine.disease eye diseases Computer Science Applications Contact lens Lens (optics) Capacitor 030104 developmental biology sense organs Resistor Antenna (radio) 030217 neurology & neurosurgery Biotechnology Biomedical engineering |
| Zdroj: | Nature Biomedical Engineering. 5:772-782 |
| ISSN: | 2157-846X |
| DOI: | 10.1038/s41551-021-00719-8 |
| Popis: | Continuous detection of raised intraocular pressure (IOP) could benefit the monitoring of patients with glaucoma. Current contact lenses with embedded sensors for measuring IOP are rigid, bulky, partially block vision or are insufficiently sensitive. Here, we report the design and testing in volunteers of a soft and transparent contact lens for the quantitative monitoring of IOP in real time using a smartphone. The contact lens incorporates a strain sensor, a wireless antenna, capacitors, resistors, stretchable metal interconnects and an integrated circuit for wireless communication. In rabbits, the lens provided measurements that match those of a commercial tonometer. In ten human participants, the lens proved to be safe, and reliably provided accurate quantitative measurements of IOP without inducing inflammation. |
| Databáze: | OpenAIRE |
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