Formation and Characterization of Fully Dilutable Microemulsion with Fatty Acid Methyl Esters as Oil Phase

Autor: Guoyong Wang, Xiumei Tai, Hongtu Wei, Wanxu Wang, Zhiping Du
Rok vydání: 2015
Předmět:
Zdroj: ACS Sustainable Chemistry & Engineering. 3:443-450
ISSN: 2168-0485
DOI: 10.1021/sc500667n
Popis: The objective of this study was to develop a green microemulsion with potential applications in the delivery system for oil-soluble solid active ingredients. A microemulsion was prepared using fatty acid methyl esters (FAMEs) as the oil phase, a mixture of alkyl polyglycoside (APG) and alkylpolyethoxy carboxylates (AEC) as the surfactant, and alkanol as a cosurfactant. The feasibility of formulating a fully water dilutable microemulsion with a green surfactant and nontoxic oil phase has been demonstrated. Pseudoternary phase diagrams were constructed by titration, and a large isotropic region was found. To expand the isotropic regions area, the effect of the mixing ratio of APG and AEC, the chain length of the cosurfactant and the oil on the isotropic area of the phase diagram were investigated systematically. As the water content increased, the continuous structural transition from water-in-oil, bicontinuous to oil-in-water microemulsion was followed by monitoring conductivity. Percolation phenomena were...
Databáze: OpenAIRE