Electrochemical Study of Flavonoids in Acetonitrile: Structure-Activity Relationships

Autor:	Carla Varela, Marcelo Videa, Netzahualcoyotl Arroyo Curras
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Antioxidant chemistry medicine.medical_treatment Inorganic chemistry medicine Square wave voltammetry Molecule Cyclic voltammetry Acetonitrile Electrochemistry Ring (chemistry) Redox
Zdroj:	ECS Transactions. 29:349-359
ISSN:	1938-6737 1938-5862
DOI:	10.1149/1.3532331
Popis:	Relations between structure, antioxidant capacity and formal redox potentials (E{degree sign}') of six flavonoids dissolved in acetonitrile were studied by cyclic voltammetry and square wave voltammetry using a glassy carbon electrode. This work shows correlation between the electrochemical parameter E{degree sign}' and the number of hydroxyl groups present in the B ring of flavonoids. Besides, it has been observed that E{degree sign}' measured as a function of B ring oxidation depends considerably on the functional groups present in the ring C of these molecules. Since antioxidant activity of flavonoids is attributed to their proton-donating, the results of this work were compared to previous reports regarding the antioxidant capacity of these compounds. Even though the antioxidant activity of flavonoids depends on several factors, the conclusions of this investigation suggest that the E{degree sign}' value should be considered as a key parameter for the evaluation of antioxidant activity.
Databáze:	OpenAIRE
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