Validation of the demographic Fetal Medicine Foundation Risk Calculator in predicting singleton antepartum stillbirth -- A retrospective case-control study

Autor: Dana A. Muin, Herbert Kiss, Nadia Attia, Karin Windsperger
Rok vydání: 2020
Předmět:
DOI: 10.22541/au.160647664.48915218/v1
Popis: Objectives: To externally validate the demographic setting of the online Fetal Medicine Foundation (FMF) Stillbirth Risk Calculator based upon maternal medical and obstetric history in a case-matched cohort. Design: Retrospective case-control study Setting: Tertiary referral hospital Population: 144 fetuses after singleton intrauterine fetal death (IUFD) and a matched control group of 247 singleton live births between 2003 and 2019 Methods: Nonparametric receiver operating characteristics (ROC) analysis was performed to predict the prognostic power of the risk score and to generate a cut-off value to discriminate best between the events of stillbirth versus live birth. Main Outcome Measures: FMF Stillbirth risk score Results: The IUFD cohort conveyed a significantly higher overall risk assessment with a median FMF Stillbirth risk score of 0.45% (0.19-5.70%) compared to live births [0.23% (0.18-1.30%); p
Databáze: OpenAIRE