Consumption of Sun-Exposed Oyster Mushrooms Help Patients Fight Tuberculosis

Autor: Donatus Nohr, Hans Konrad Biesalski, Tibebeselassie Seyoum Keflie, Ashagrie Zewdu Woldegiorgis, Aregash Samuel, Christine Lambert
Rok vydání: 2021
Předmět:
Zdroj: Asian Journal of Complementary and Alternative Medicine. 9
ISSN: 2347-3894
DOI: 10.53043/2347-3894.acam90007
Popis: Introduction: Tuberculosis (TB) is an airborne infectious disease that usually affects the lungs leading to severe coughing, fever, and chest pains. Objective: This study aimed to assess the effects of consuming sun-exposed mushrooms on the treatment outcomes of TB Methods: Participants were TB patients and categorized into block-1 (32) and block-2 (32) based on their willingness to consume sandwich bread containing sun-exposed oyster mushrooms. Blood and sputum samples were taken at the beginning (Day 0) and end of the study (4th month). Assays of 25-hydroxy (OH) D, cytokines, LL-37, and CRP were performed using Enzyme Linked- Immunosorbent Assay (ELISA) technique, and mycobacterial cultures were performed using Lowenstein Jensen media. A p-value less than 0.05 was considered significant. Results: Consumption of the sandwich bread induced a 27.8% increase in the mean serum 25(OH)D level with 35.5% and 32.3% reduction in the proportion of vitamin D deficiency (VDD) and insufficiency (VDI), respectively. There were progressive changes in TB score (mean } SD of 2.6 } 1.8; 95% CI of 1.95 to 3.17; p
Databáze: OpenAIRE