| Autor: |
Ogbuinya Oliver Onukwube, Jombo Sunday Emmanuel, Egede John Okafor, Onoh Robinson C, Obi Vitus Okwuchukwu, Nwali Silas Alegu |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
International Research Journal of Obstetrics and Gynecology. :28 |
| ISSN: |
2639-6009 |
| DOI: |
10.28933/irjog-2020-04-1506 |
| Popis: |
Background: Postpartum Haemorrhage (PPH) still remains a major cause of maternal mortality despite adequate knowledge of its causes and treatment. Oxytocin administration is one of the major components of active management of third stage of labour (AMTSL). Evidence suggest benefit of misoprostol as an adjunct however optimal dose is yet to be determine considering the dose depended side effect profile of misoprostol. . Objective: This study evaluated the efficacy and side effect profile of 200µg versus 400µg of prophylactic sublingual misoprostol as adjunct to AMTSL among parturient at risk for PPH. Methods: This was a double blinded, single centre, randomized controlled trial involving two hundred and forty parturient with 2.1% drop out rate , thus 235 of them were analyzed; 117 (48.8%) and 118(49.2%) for 200 and 400 microgram group respectively. Data was analyzed using Statistical Package for Social Science (IBM SPSS) software (version 24, Chicago II, USA). Continuous variables were presented as mean and standard deviation (Mean ± 2SD), while categorical variables were presented as numbers and percentages. Chi-square test (X2) was used for comparison between groups for qualitative variables while t-test was used for comparison between groups for quantitative variables. A difference with a P value |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
