Phenolic Antioxidants fromCasimiroa edulis. Leaves
| Autor: | Amani S. Awaad, Derek J. Maitland, Tom J. Mabry, N.H. El-Sayed |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Pharmacology
chemistry.chemical_classification Chromatography biology Electrospray ionization Casimiroa Flavonoid Ethyl acetate Pharmaceutical Science General Medicine DEPT biology.organism_classification Flavones chemistry.chemical_compound Complementary and alternative medicine chemistry Drug Discovery Molecular Medicine Organic chemistry Trolox Phenols |
| Zdroj: | Pharmaceutical Biology. 44:258-262 |
| ISSN: | 1744-5116 1388-0209 |
| DOI: | 10.1080/13880200600713899 |
| Popis: | In the present current, quercetin and its 3-O.-rutinoside, the ethyl acetate and ethanol extracts, and two new flavones from Casimiroa edulis. Llave et Lex (Rotaceae) were tested for their antioxidant activity via scavenging by the ABTS˙+ [2,2′-azinobis(3-ethylbenzothiazolone-6-sulfonic acid)]free radical. Among all the tested fractions and compounds, the ethanol extract exhibited the strongest antioxidant activity followed by EtOAc extract, giving 842 and 712 µM Trolox equivalents/g dry weight, respectively. Moderate activities were detected for the other tested materials. The two new flavones were identified as 5-methoxy-6-hydroxyflavone and its 6-O.-β.-D-glucoside. The structure elucidation was based on UV, electrospray ionization mass spectrometry (ESIMS), 1H and 13C NMR, proton-proton correlation spectroscopy (1H-1H COSY), distortionless enhancement by polarization transfer (DEPT), heteronuclear single quantum coherence (HSQC), and heteronuclear multiple bond correlations spectrum (HMBC). |
| Databáze: | OpenAIRE |
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