Application of THz Fast Frequency Sweep Spectrometer for Investigation of Chemical Composition of Blood
| Autor: | V. A. Anfert’ev, Elena G. Domracheva, S. I. Pripolzin, A. A. Yablokov, M. B. Chernyaeva, Vladimir L. Vaks, Anna Maslennikova |
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| Rok vydání: | 2019 |
| Předmět: |
010302 applied physics
Medical diagnostic Radiation Materials science Spectrometer business.industry Terahertz radiation Thermal decomposition Evaporation Condensed Matter Physics 01 natural sciences Sweep frequency response analysis Terahertz spectroscopy and technology 010309 optics 0103 physical sciences Optoelectronics Electrical and Electronic Engineering business Instrumentation Chemical composition |
| Zdroj: | Journal of Infrared, Millimeter, and Terahertz Waves. 41:1114-1120 |
| ISSN: | 1866-6906 1866-6892 |
| DOI: | 10.1007/s10762-019-00656-3 |
| Popis: | One of the approaches with a basically new potential for the diagnostics and treatment of socially significant diseases, such as diabetes and oncologic diseases, is based on detecting the metabolites which are indicators of diseases, including the early stage. The results of analyzing the composition of biological liquid vapor (such as blood) samples by the method of high-resolution terahertz spectroscopy based on the fast frequency sweep approach are presented. The fast frequency sweep spectrometer of the 118 ÷ 178 GHz frequency range was elaborated. A multicomponent gas mixture of products of blood evaporation and thermal decomposition at heating up to 240 °C was analyzed. A number of substances that are products of evaporation and thermal decomposition of blood components were detected. Some processes of the appearance of specific substances were discussed. The proposed approach is promising for developing a method of noninvasive medical diagnostics of pathologies and diseases, including socially significant ones. |
| Databáze: | OpenAIRE |
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