Motor Unit Number Index of the Upper Trapezius: A Meta-Analysis and Cross-sectional Study of Its Reliability

Autor:	Agessandro Abrahao, Liane Phung, David Fam, Marcio Luiz Escorcio-Bezerra, Lawrence R. Robinson, Kelvin E. Jones, Lorne Zinman
Rok vydání:	2023
Předmět:	Neurology Neurology (clinical) General Medicine
Zdroj:	Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. :1-5
ISSN:	2057-0155 0317-1671
DOI:	10.1017/cjn.2023.20
Popis:	Motor unit number index of the upper trapezius (MUNIX-Trapezius) is a candidate biomarker for bulbar lower motor neuron function; however, reliability data is incomplete. To assess MUNIX-Trapezius reliability in controls, we conducted a systematic review, a cross-sectional study (n = 20), and a meta-analysis. We demonstrated a high inter- and intra-rater intraclass correlation (0.86 and 0.94, respectively), indicating that MUNIX-Trapezius is reliable with between-study variability moderated by age and MUNIX technique. With further validation, this measure can serve as a disease monitoring and response biomarker of bulbar function in the therapeutic development for amyotrophic lateral sclerosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2395d879fdee1cb4d7b576a7998d5b1b https://doi.org/10.1017/cjn.2023.20 Zobrazit plný text záznamu