The potential of intranasal delivery of nanocrystals in powder form on the improvement of zaleplon performance: in-vitro, in-vivo assessment
| Autor: | Ehab A. Hosni, Omaima N. El Gazayerly, Randa Latif, Rana R. Makar |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pharmacology
Chemistry Organic Chemistry Pharmaceutical Science 02 engineering and technology 021001 nanoscience & nanotechnology 030226 pharmacology & pharmacy Bioavailability 03 medical and health sciences Zaleplon 0302 clinical medicine Drug Discovery medicine Nasal administration In vitro in vivo 0210 nano-technology medicine.drug |
| Zdroj: | Drug Development and Industrial Pharmacy. 47:268-279 |
| ISSN: | 1520-5762 0363-9045 |
| DOI: | 10.1080/03639045.2021.1879834 |
| Popis: | The present work focuses on improving zaleplon (ZAP) performance through nanosizing its insoluble particles which were then delivered intranasally in powder form. Since nanopowders have an exceptio... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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