Characteristics and features of the formation of humoral immunity after immunization with Sputnik V and Vero Cell vaccines

Autor: T. V. Amvrosieva, I. V. Belskaya, Z. F. Bohush, N. V. Paklonskaya, Yu. B. Kaltunova, O. N. Kazinetz
Rok vydání: 2021
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of Belarus, Medical series. 18:456-465
ISSN: 2524-2350
1814-6023
DOI: 10.29235/1814-6023-2021-18-4-456-465
Popis: The presented work contains an analysis of seroprevalence, tension, and duration of post-vaccination immunity to the SARS-CoV-2 coronavirus in the residents of the Republic of Belarus after immunization with two vaccine preparations available in the country: Sputnik V and Vero Cell.It was found that seroconversion after the injection of the Vero Cell vaccine occurred significantly later than after the Sputnik V vaccine (p 65 years). The proportion of individuals with the highest IgG score for the SARS-CoV-2 S protein was higher after the Sputnik V administration compared to that in response to the Vero Cell vaccine (p 65 years). The proportion of individuals with the highest IgG score for the SARS-CoV-2 S protein was higher after the Sputnik V administration compared to that in response to the Vero Cell vaccine (p The obtained results complement the accumulated world science and practical information on the problem of the postvaccination immunity formation in the context of the use of different drugs against COVID-19.
Databáze: OpenAIRE