Immortalization of Hepatocytes through Targeted Deregulation of the Cell Cycle

Autor:	M. Strauss, G. S. Jennings
Rok vydání:	2007
Předmět:	Genetic enhancement Retinoblastoma protein Biology Cell cycle law.invention Cell biology Cell culture law biology.protein Recombinant DNA medicine Hepatocyte growth factor Cell Cycle Protein medicine.drug
Zdroj:	Cell Engineering ISBN: 9780792357902
DOI:	10.1007/978-0-585-37971-5_10
Popis:	The generation of continuously proliferating hepatocytes expressing differentiated functions has been a goal long sought after by workers in the fields of liver toxicology and pathology, in recombinant protein technology and in gene therapy and medicine. The requirements of these disciplines will define the parameters for selecting an immortalization strategy and will ultimately pass judgement on the success of newly created cell lines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::236ba5de23b4329be6d8efcda28dcd91 https://doi.org/10.1007/978-0-585-37971-5_10 Zobrazit plný text záznamu