| Autor: |
MAXIMILIAN MAECHLER, LUKAS SPRENGER, ARTHUR MADER, BARBARA LARCHER, ALEXANDER VONBANK, ANDREAS LEIHERER, AXEL MUENDLEIN, HEINZ DREXEL, CHRISTOPH H. SAELY |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Diabetes. 71 |
| ISSN: |
0012-1797 |
| DOI: |
10.2337/db22-429-p |
| Popis: |
Elevated pro-B type natriuretic peptide (pro-BNP) has been found to be a strong marker of cardiovascular risk in several high-risk populations. However, the power of pro-B type natriuretic peptide (pro-BNP) to predict major cardiovascular events (MACE) and mortality in patients with the combination of established cardiovascular disease and type 2 diabetes (T2DM) is unclear and is addressed in the present study. We enrolled 873 patients with established cardiovascular disease, 579 with angiographically proven stable CAD and 294 with sonographically proven peripheral artery disease. Prospectively, cardiovascular events were recorded over a mean follow-up period of 7.9±3.6 years. At baseline, pro-BNP was significantly higher in patients with T2DM (n=285) than in those who did not have diabetes (1010±26vs. 727±2327 mg/dl; p=0.003) . During follow-up, 257 patients suffered MACE; the event rate was significantly higher in patients with T2DM than in subjects without T2DM (37.8 vs. 26.0%; p Disclosure M.Maechler: None. L.Sprenger: None. A.Mader: None. B.Larcher: None. A.Vonbank: None. A.Leiherer: None. A.Muendlein: None. H.Drexel: None. C.H.Saely: None. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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