Elimination of large pyroninophilic cells by the action of phytohemagglutinin

Autor:	S. N. Bykovskaya, A. M. Shepelenko, A. F. Bykovskii
Rok vydání:	1975
Předmět:	education.field_of_study Population General Medicine Mitochondrion Biology Ribosome General Biochemistry Genetics and Molecular Biology Cell biology medicine.anatomical_structure Biochemistry Cytoplasm Precursor cell Organelle medicine education Incubation Nucleus
Zdroj:	Bulletin of Experimental Biology and Medicine. 80:1116-1119
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00799907
Popis:	Disappearance of medium-sized and large pyroninophilic lymphocytes, adsorbed on the surface of target cells, was shown to take place after the addition of phytohemagglutinin (PHA). After incubation for 45 min in the presence of PHA no cisterns of the granular endoplasmic reticulum could be found in the lymphocytes and the mitochondria were fewer in number. Cells labeled with thymidine-H3 had practically completely disappeared. A population of small lymphocytes with smooth outlines and pale cytoplasm, poor in organelles, and with ribosomes scattered freely in them appeared. After incubation for 24–48 h they were transformed into blast cells, larger cells with a pale nucleus and pale cytoplasm, in which no cisterns of the granular endoplasmic reticulum could be found.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::234c496e034d4a13c82d792c1a2e3da6 https://doi.org/10.1007/bf00799907 Zobrazit plný text záznamu Full text from SpringerLink