The Content of Peripheral and Integral Proteins in Vertebrate Brain Microsomal Membranes

Autor:	T. N. Medvedeva
Rok vydání:	2005
Předmět:	biology Physiology Peripheral membrane protein Vertebrate Biochemistry Membrane Membrane protein biology.animal Microsome Receptor Integral membrane protein Ecology Evolution Behavior and Systematics Ion channel
Zdroj:	Journal of Evolutionary Biochemistry and Physiology. 41:157-161
ISSN:	1608-3202 0022-0930
DOI:	10.1007/s10893-005-0049-8
Popis:	The content of peripheral and integral proteins in brain microsomal membranes in 11 species of vertebrates is studied. The amount of peripheral proteins does not exceed one third of the total protein, whereas integral proteins account for the main mass of proteins of microsomal membranes in the brain of animals at all levels of the vertebrate organization. Predominance of integral proteins can be considered as an indicator of a significant rigidity, high stability of brain membranes, and predominance in neuronal membranes of complex receptor proteins, ion channels and pumps, as well as ion exchangers. Microsomal membranes in the brain of reptiles are characterized by a higher content of peripheral and integral Triton-soluble proteins in comparison with other classes of animals. The possibility to use data on chemical composition of the brain microsomal membranes for study of congener relationships of vertebrates is considered.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::234b87e84fe2b62a07b9881db22a8be2 https://doi.org/10.1007/s10893-005-0049-8 Zobrazit plný text záznamu Full text from SpringerLink