The zaragozic acids: Structure elucidation of a new class of squalene synthase inhibitors
| Autor: | Claude Dufresne, Robert A. Reamer, Vanmiddlesworth Frank L, Otto D. Hensens, Deborah L. Zink, Jerrold M. Liesch |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
chemistry.chemical_classification
ATP synthase biology Bicyclic molecule Chemistry Stereochemistry Organic Chemistry Acetal Zaragozic acid Nuclear magnetic resonance spectroscopy Tricarboxylic acid Biochemistry chemistry.chemical_compound Squalene Drug Discovery biology.protein Two-dimensional nuclear magnetic resonance spectroscopy |
| Zdroj: | Tetrahedron Letters. 34:399-402 |
| ISSN: | 0040-4039 |
| Popis: | Structures of two novel fungal metabolites, zaragozic acids A (1) and B (2), characterized by a novel 2,8-dioxobicyclo[3.2.1] octane-4,6,7-trihydroxy-3,4,5-tricar☐ylic acid core, are proposed predominantly on the basis of 2D NMR. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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