| Autor: |
Donald M. Brunette, Ning-Ping Huang, Marcus Textor, Karl-Ludwig Eckert, Erich Wintermantel |
| Rok vydání: |
2001 |
| Předmět: |
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| Zdroj: |
Engineering Materials ISBN: 9783642631191 |
| DOI: |
10.1007/978-3-642-56486-4_19 |
| Popis: |
The high biocompatibility of titanium is useful not only in load-bearing implants, but also in implants which are intended to stimulate metabolic responses, such as implantable cell-carriers, and also in cell-culture substrates for in vitro culture and tissue engineering. A potential application is transplantation of liver cells. Implant-able cell-carriers which should serve to transplant liver cells into a diseased organism require the use of materials which do not induce the formation of a dense fibrous tissue capsule at the implantation site. Such a dense capsule formation would cut off transplanted cells from their nutrition supply with a fatal outcome for the cells. Moreover, as an implant can lead to neoformation of blood vessels [1] the carrier material should be of the highest biocompatibility to enable the ongrowth of vascularized, healthy tissue which can establish a long-term vascular supply for transplanted cells. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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