Popis: |
Human blood coagulation factor 13, the fibrin stabilizing factor, is a zymogen which after activation by thrombin and calcium ions catalyses the formation of γ -glutamyl- e -lysine cross links between fibrin molecules (Losowsky and Miloszewski, 1977). Factor 13 consists of two A subunits and two B subunits (A2B2) (Schwartz et al 1973). Both A and B subunits are found in plasma but only B subunits in serum. The B subunit has no enzymatic activity and may serve as a carrier molecule in plasma (Schwartz et al 1973). |