Prolongation of heart allograft survival in rats by interferon-specific antibodies and low dose cyclosporin A
Autor: | M. Gigou, Henri Bismuth, F. Crafa, Michael G. Tovey, M. Reynes, B Fabiani, Jean Gugenheim |
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Rok vydání: | 1992 |
Předmět: | |
Zdroj: | Transplant International Official Journal of the European Society for Organ Transplantation ISBN: 9783540553427 |
Popis: | Interferons (IFNs) are important cytokines which exhibit antiviral, antitumor, anticellular, as well as immunoregulatory activities [1]. Among these multiple activities, IFNs are potent inducers of MHC antigen expression of a great variety of cells [2–4], helper and maturation factors in B-cell antibody production [5], and macrophage function [6]. IFNs may therefore play a critical role in triggering antigen recognition and allograft rejection. |
Databáze: | OpenAIRE |
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