Prolongation of heart allograft survival in rats by interferon-specific antibodies and low dose cyclosporin A

Autor:	M. Gigou, Henri Bismuth, F. Crafa, Michael G. Tovey, M. Reynes, B Fabiani, Jean Gugenheim
Rok vydání:	1992
Předmět:	Heart transplantation biology business.industry medicine.medical_treatment Immunosuppression Interferon Cyclosporin a Immunology medicine biology.protein Macrophage Inducer Antibody business Function (biology) medicine.drug
Zdroj:	Transplant International Official Journal of the European Society for Organ Transplantation ISBN: 9783540553427
Popis:	Interferons (IFNs) are important cytokines which exhibit antiviral, antitumor, anticellular, as well as immunoregulatory activities [1]. Among these multiple activities, IFNs are potent inducers of MHC antigen expression of a great variety of cells [2–4], helper and maturation factors in B-cell antibody production [5], and macrophage function [6]. IFNs may therefore play a critical role in triggering antigen recognition and allograft rejection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2333c4db1d4da286591f0c68002a1347 https://doi.org/10.1007/978-3-642-77423-2_134 Zobrazit plný text záznamu