On the mechanism of formation of dimeric and reduced products from an α-halo amide with sodium methoxide

Autor:	K. Lempert, Zs. Váli, Gábor Tóth, Gy. Simig, József Tamás
Rok vydání:	1978
Předmět:	chemistry.chemical_compound Reduced product chemistry Amide Dimer Organic Chemistry Drug Discovery Polymer chemistry Organic chemistry Halo Biochemistry Sodium methoxide Mechanism (sociology)
Zdroj:	Tetrahedron. 34:2371-2375
ISSN:	0040-4020
DOI:	10.1016/0040-4020(78)89053-x
Popis:	Treatment of 2-bromo-N,N-dimethyl-2,2-diphenylacetamide 1 with sodium methoxide in 2,2-dimethoxypropane furnishes mixtures of the reduced product 2 and the dimer 5 . Crossing experiments have shown that 2 is not a precursor of 5 , supporting thereby the S RN 1 mechanism for the formation of both 5 and 2 .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2331d7a8adc5f2ce218a9dac586f4758 https://doi.org/10.1016/0040-4020(78)89053-x Zobrazit plný text záznamu