Pregnancy or Uremia? – Case Report and Review of Conception, Pregnancy, and Complications in Peritoneal Dialysis Patients

Autor: Anil Regmi, Amarpreet Sandhu, Antonios H. Tzamaloukas, David Buchwald
Rok vydání: 2014
Předmět:
Zdroj: Cureus.
ISSN: 2168-8184
DOI: 10.7759/cureus.206
Popis: Pregnancy is infrequent in women undergoing renal replacement therapy (RRT) and may lead to serious maternal and fetal complications. Although rates of conception have increased for women on hemodialysis (HD), overall conception rates for women on renal RRT remain low. Incidence of pregnancy in peritoneal dialysis (PD) patients has been reported as 1.1% in a study that followed 1,699 patients for four years. The lower pregnancy rate in women on PD is due to mechanical factors on top of functional and physiological abnormalities. In the United States, the majority of the pregnant women undergoing PD are transitioned to HD to improve fetal outcomes. Due to negligible rates of conception and to similar symptoms, early pregnancy symptoms in patients with advanced chronic kidney disease (CKD) approaching RRT can be confused with uremic symptoms. Once pregnancy is established, multilevel changes need to be made in the management of women on PD. Coordinated care by nephrologists, neonatologists, obstetricians, and nutritionists can lead to better outcomes. We present a case of pregnancy in a woman with advanced CKD where PD was continued with good outcomes. The pregnancy was terminated by a full-term natural delivery. In addition, we review the diagnosis, management, outcomes, and complications of pregnancy in women on PD.
Databáze: OpenAIRE