Cinchona and Quinine: A Remarkable Anniversary

Autor:	L. J. Bruce-Chwatt
Rok vydání:	1990
Předmět:	Quinine biology Traditional medicine Ecology business.industry Cinchona biology.organism_classification medicine.disease History and Philosophy of Science visual_art Natural source visual_art.visual_art_medium medicine Bark business Social Sciences (miscellaneous) Malaria medicine.drug
Zdroj:	Interdisciplinary Science Reviews. 15:87-93
ISSN:	1743-2790 0308-0188
DOI:	10.1179/isr.1990.15.1.87
Popis:	The use of the bark of the 'fever tree', cinchona, to cure intermittent fevers was first described in print by an Augustian monk in 1638, just over 350 years ago. The discovery and the first records are here chronicled. As such fevers were widespread, demand for the bark increased greatly, and attempts were made to establish cinchona tree plantations in tropical zones, most of them unsuccessfully. Only Dutch commercial production in what is now Indonesia was profitable. Chemical synthesis of antimalarial drugs reduced natural production of quinine for a time, but as drug resistance among the parasites that cause the malaria has increased, culvitation of the natural source has again become important.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::23296df0f445d3f965191ed2e6c7b2d6 https://doi.org/10.1179/isr.1990.15.1.87 Zobrazit plný text záznamu