Synthesis and antiproliferative activity of 3-substituted 1H-indole [3,2-d]-1,2,3-triazin-4 (3H)-ones

Autor:	Mario Castelli, Marinella Roberti, Laura Garuti, Tiziana Rossi, M Malagoli
Rok vydání:	1998
Předmět:	Pharmacology Indole test Chemistry Daunorubicin Organic Chemistry General Medicine medicine.disease Chronic myeloid leukaemia Chemical synthesis In vitro Lymphoma Daunorubicina D-1 immune system diseases hemic and lymphatic diseases Drug Discovery medicine Cancer research neoplasms medicine.drug
Zdroj:	European Journal of Medicinal Chemistry. 33:43-46
ISSN:	0223-5234
DOI:	10.1016/s0223-5234(99)80074-9
Popis:	Some 3-substituted indole-triazin-4-ones were synthesized. Their antiproliferative activity against chronic myeloid leukaemia and non-Hodgkin lymphoma human cells was compared in vitro with that of daunorubicin. One compound appeared to be very effective against human CML.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2328de20780fd81fc936b6b02841db47 https://doi.org/10.1016/s0223-5234(99)80074-9 Zobrazit plný text záznamu Full Text from ScienceDirect