All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein
| Autor: | Ilya Frolov, Tatiana Agback, Oksana Palchevska, Francisco Dominguez, Alexander Lomzov, Peter Agback, Elena I. Frolova |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of Virology. 97 |
| ISSN: | 1098-5514 0022-538X |
| Popis: | The nsp1 of SARS-CoV-2 is a multifunctional protein that modifies the intracellular environment for the needs of viral replication. It is responsible for the development of translational shutoff, and its expression alone is sufficient to cause a cytopathic effect (CPE). |
| Databáze: | OpenAIRE |
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