Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data

Autor:	Constance A. Benson, Otto O. Yang, Sarah B Doernberg, Robert Grossberg, Jing Wang, David C. Lye, Philip O Ponce, Cameron R. Wolfe, Richard T. Davey, Shannon K. Gallagher, Lori E. Dodd, Jocelyn Voell, Rekha R. Rapaka, William R. Short, Noreen A. Hynes, Catharine I. Paules
Rok vydání:	2021
Předmět:	Microbiology (medical) Mechanical ventilation medicine.medical_specialty Coronavirus disease 2019 (COVID-19) business.industry medicine.medical_treatment Infectious Diseases Risk groups Treatment trial Oxygen breathing Emergency medicine Cohort Post-hoc analysis medicine Treatment effect business
Zdroj:	Clinical Infectious Diseases. 74:1260-1264
ISSN:	1537-6591 1058-4838
Popis:	This post hoc analysis of the Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1 (ACTT-1) shows a treatment effect of remdesivir (RDV) on progression to invasive mechanical ventilation (IMV) or death. Additionally, we create a risk profile that better predicts progression than baseline oxygen requirement alone. The highest risk group derives the greatest treatment effect from RDV.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::230b61c921454b0c03a80539a1f29583 https://doi.org/10.1093/cid/ciab695 Zobrazit plný text záznamu