ChemInform Abstract: Prostanoids: Synthesis of Enantiomers of 15-Deoxy-16-hydroxy-16- methylprostaglandin E1

Autor: Jaroslav Paleček, Václav Kozmík, Miroslav Terinek
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 28
ISSN: 0931-7597
DOI: 10.1002/chin.199751266
Popis: Four optically pure isomers of methyl 11,16-dihydroxy-16-methyl-9-oxoprost-13-enoate (1a-1d) were synthesized using an approach reverse to the classical Corey procedure, the key intermediates being the easily accessible (-)- and (+)-enantiomers of the Corey lactone, 2a and 2b.
Databáze: OpenAIRE