Copper(II) Triflate-Catalyzed Nucleophilic Substitution of Propargylic Acetates with Enoxysilanes. A Straightforward Synthetic Route to Polysubstituted Furans

Autor:	Jing-liang Yu, Hui-juan Liu, Zhuang-Ping Zhan, Shao-pei Wang, Xu-bin Cai, Yuan-yuan Cui
Rok vydání:	2007
Předmět:	chemistry.chemical_classification Substitution reaction chemistry.chemical_compound Ketone Copper(II) triflate chemistry Nucleophilic substitution chemistry.chemical_element Organic chemistry General Chemistry Copper Trifluoromethanesulfonate Catalysis
Zdroj:	Advanced Synthesis & Catalysis. 349:2097-2102
ISSN:	1615-4169 1615-4150
DOI:	10.1002/adsc.200700234
Popis:	A novel and efficient procedure for the synthesis of γ-alkynyl ketones by the nucleophilic substitution of propargylic acetates with enoxysilanes in the presence of a catalytic amount of Copper(II) triflate, has been developed. The substitution reaction can be followed by a 4-toluenesulfonic acid-catalyzed cyclization without purification of the γ-alkynyl ketone intermediates, offering a straightforward synthetic route to polysubstituted furans.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::22d5c4b4ee6442a965d1f2cd4a32212b https://doi.org/10.1002/adsc.200700234 Zobrazit plný text záznamu Plný text