A probable conformational difference between recombinant and urinary erythropoietins
| Autor: | Eugene Goldwasser, Charles K.-H. Kung |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
chemistry.chemical_classification
Glycosylation Chemistry Urinary system fungi Significant difference Trypsin Biochemistry Molecular biology law.invention chemistry.chemical_compound Structural Biology law Erythropoietin medicine Recombinant DNA Posttranslational modification Glycoprotein Molecular Biology medicine.drug |
| Zdroj: | Proteins: Structure, Function, and Genetics. 28:94-98 |
| ISSN: | 1097-0134 0887-3585 |
| Popis: | Urinary and recombinant human erythropoietin differ with respect to ease of iodination, inactivation by iodination, second derivative and circular dichroic spectra, rate of inactivation by trypsin and glycosylation pattern. All of these differences are compatible with a significant difference in conformation of these two forms of erythropoietin. © 1997 Wiley-Liss Inc. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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