0858 Impact Of Actigraphic Sleep Measures On Ambulatory Cognitive Performance In A Community-Based Sample Of Older Adults

Autor: Carol A. Derby, June Jiao, Martin J. Sliwinski, Ruixue Zhaoyang, Orfeu M. Buxton
Rok vydání: 2020
Předmět:
Zdroj: Sleep. 43:A327-A327
ISSN: 1550-9109
0161-8105
DOI: 10.1093/sleep/zsaa056.854
Popis: Introduction Few longitudinal studies link objectively assessed sleep and cognition, especially day to day differences in sleep as they relate to daily cognitive performance in ecologically-valid, natural environments. We examine the associations of sleep (actigraphy) with ambulatory ecological momentary assessments (EMA) of cognitive performance. Methods Analyses involved 225 participants enrolled in The Einstein Aging Study, a community based longitudinal cohort of older adults free of dementia at enrollment (Mage=77.27 years; 33% males; 47% Caucasian, 39% African American, 13% Hispanic). We examined between-person associations between actigraphic sleep duration and wake after sleep onset (WASO) with mean and variability across the day in cognitive performance. Cognitive performance was assessed via validated, smartphone-based EMA over a mean of 18 days. Six assessments/day included Symbol Match (processing speed), Color Dot (working memory), and Color Shape (memory binding). Models controlled for age, gender, ethnicity, education (years), clinically assessed mild cognitive impairment, and learning effects. Actigraphy data was collected throughout the study period. Results Sleep duration had a significant effect on within-person variability on ambulatory cognition: Color Dot, Symbol Match, and Color Shape (all p’s Conclusion Ambulatory cognitive performance assessed using EMA was related to actigraphic sleep. Poor sleep health may be a target for prevention of early cognitive changes that may precede onset of cognitive impairment and AD. Support Research was supported by the National Institute on Aging (NIA) award numbers P01AG003949 and R01AG056538.
Databáze: OpenAIRE
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