| Autor: | Tidly Ping, Sandra M. Wice, Linda M. Hiebert, Ronald E. Hileman, Tfilay Polat, Robert J. Linhardt |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Drug
medicine.medical_specialty media_common.quotation_subject Sodium Pharmaceutical Science chemistry.chemical_element Pharmacokinetics Oral administration Sucrose octasulfate Internal medicine medicine Pharmacology (medical) Tissue distribution media_common Pharmacology business.industry Organic Chemistry Heparin biochemical phenomena metabolism and nutrition enzymes and coenzymes (carbohydrates) Sucralfate Endocrinology chemistry bacteria Molecular Medicine business Biotechnology medicine.drug |
| Zdroj: | Pharmaceutical Research. 19:838-844 |
| ISSN: | 0724-8741 |
| Popis: | Purpose. Aluminum sucrose octasulfate (SOS) is used clinically to prevent ulcers. Under physiologic conditions, the sodium salt of this drug can be formed. Our objective was to determine whether sodium SOS was absorbed when administered orally. In addition to furthering our understanding of aluminum SOS, this study also aimed to clarify how other polyanionic drugs, such as heparin and low-molecular-weight heparins, are absorbed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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