Autor: | O. V. Smirnova, R. L. Bogorad, N. I. Shono, A. V. Kulikov, L. V. Platonova, T.Y. Zenkova, E.I. Gal'perin, A. A. Rozenkrants |
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Rok vydání: | 2003 |
Předmět: |
medicine.medical_specialty
business.industry Prolactin receptor General Medicine Secondary liver cancer Jaundice medicine.disease General Biochemistry Genetics and Molecular Biology Prolactin Endocrinology Cholestasis Internal medicine Etiology medicine medicine.symptom Receptor business Indirect immunoperoxidase assay |
Zdroj: | Bulletin of Experimental Biology and Medicine. 135:566-569 |
ISSN: | 0007-4888 |
DOI: | 10.1023/a:1025429318932 |
Popis: | Indirect immunoperoxidase assay and computer analysis of photographic images revealed more intensive expression of prolactin receptors in hepatocytes of women compared to men. The intensity of expression was maximum in secondary liver cancer, high in obstructive jaundice of different etiology, and less pronounced in cholelithiasis. The expression of prolactin receptors in cholangiocytes was higher than in hepatocytes and was maximum during obstructive jaundice of different etiology. Cells of secondary tumors were characterized by low expression, while distant hepatocytes most intensively expressed prolactin receptors. |
Databáze: | OpenAIRE |
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