Top 10 Drugs Most Commonly Used for GI Motility Disorders
| Autor: | Mark Reichelderfer, Luis D. Lomeli, Eric A. Gaumnitz |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
education.field_of_study
medicine.medical_specialty business.industry Population Pharmacology medicine.disease Lubiprostone chemistry.chemical_compound Pharmacotherapy chemistry Alosetron medicine Esophageal spasm Gastroparesis business education Intensive care medicine Linaclotide Irritable bowel syndrome medicine.drug |
| Zdroj: | Gastrointestinal Motility Disorders ISBN: 9783319593500 |
| DOI: | 10.1007/978-3-319-59352-4_39 |
| Popis: | Disorders of gastrointestinal motility are among the most common and difficult clinical problems faced by practicing gastroenterologists. The purpose of this chapter is to review currently available drugs for the treatment of these conditions. Structures involved include the esophagus, stomach, and intestine. Atypical chest pain can arise from diffuse esophageal spasm and is treated with calcium channel blockers, nitrates, and other antispasm drugs such as phosphodiesterase inhibitors. Gastroparesis is managed with prokinetics although the need for new therapies is clear. Irritable bowel syndrome affects up to 30% of the population with anticholinergics and multiple new drugs improving patient outcomes. A new indication for drug therapy is opiate-induced constipation. Fortunately, given the complexity of motility problems, this is a field of rapid advancement with multiple new drugs in the pipeline. |
| Databáze: | OpenAIRE |
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