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Publisher Summary This chapter discusses the recent advances made in genetics and molecular biology as a result of studies carried out in Neurospora crassa, a filamentous fungus. Three reviews that appeared in recent years describe the current data on transformation in fungi. However, no attempt is made until now to review at any length this area of Neurospora molecular biology. Neurospora is an ideal organism for studies in genetics and molecular biology. The chapter tabulates the relative complexity of the Neurospora genome. Neurospora possesses a spectrum of nuclear, mitochondrial, and plasmid genetic systems that are amenable to analyses by various molecular biology methods. Neurospora is also capable of heterokaryon formation, a trait that renders the determination of the dominance and recessiveness of alleles easy. It is obvious that further investigation of all aspects of the molecular biology of Neurospora as discussed in the chapter can provide new insights into the intricacies of nature and the mechanisms responsible for the maintenance of extra genes. |
