| Popis: |
The metal nanoparticles synthesized by green synthesis can be used as an alternative strategy to overcome antimicrobial resistance. In this study, metal nanoparticles were synthesized using Proteus penneri, a Gram-negative rod-shaped bacteria that facilitated the reduction of metals into their respective nanoparticles. Biosynthesized particles were characterized by DLS, SEM, UV-visible spectroscopy. It was selected for the study and was found to have the ability to form silver, gold, chromium, copper, nickel and zinc nanoparticles as observed by change in color of the reaction. The spectral analysis confirmed the presence of carbonyl groups from the amino acid residues wherein proteins have the stronger capability to bind the metal that probably aid in the formation of metal nanoparticles. Antibacterial property reveals that silver, gold and chromium based metal nanoparticle are best suitable candidates to overcome antibiotic resistance. Zn and Au showed significant anti-inflammatory property by inhibiting PLA2, further they could inhibit angiogenesis there by exhibiting anti cancerous property |
